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Integrity - use of values or principles to guide action in the situation at hand.

Below are links and discussion related to the values of freedom, hope, trust, privacy, responsibility, safety, and well-being, within business and government situations arising in the areas of security, privacy, technology, corporate governance, sustainability, and CSR.

Most scientific papers are probably wrong (and I think they should be), 30.8.05


Most published scientific research papers are wrong, according to a new analysis. Assuming that the new paper is itself correct, problems with experimental and statistical methods mean that there is less than a 50% chance that the results of any randomly chosen scientific paper are true.

John Ioannidis, an epidemiologist at the University of Ioannina School of Medicine in Greece, says that small sample sizes, poor study design, researcher bias, and selective reporting and other problems combine to make most research findings false. But even large, well-designed studies are not always right, meaning that scientists and the public have to be wary of reported findings.

"We should accept that most research findings will be refuted. Some will be replicated and validated. The replication process is more important than the first discovery," Ioannidis says.

In the paper, Ioannidis does not show that any particular findings are false. Instead, he shows statistically how the many obstacles to getting research findings right combine to make most published research wrong.

[...] [CLB: The targeted readership, other researchers, understand this point generally. Publishing reserach results is expected to lead to discussion, further research on the hypothesis, and often refutation, with improved or modified hypotheses emerging. The problem arises from the media and laypersons use of published research. Media is likely to publish startling, 'newsworthy' results to make headlines. They don't include the rest of the scientific process. What's missing in the popular press: repeating the results, relating the results to other findings, systematic analysis and synthesis of the results, and taking sample-based results in a reliable way into an understanding of how these actually relate to the more general population.]


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"We shall need compromises in the days ahead, to be sure. But these will be, or should be, compromises of issues, not principles. We can compromise our political positions, but not ourselves. We can resolve the clash of interests without conceding our ideals. And even the necessity for the right kind of compromise does not eliminate the need for those idealists and reformers who keep our compromises moving ahead, who prevent all political situations from meeting the description supplied by Shaw: "smirched with compromise, rotted with opportunism, mildewed by expedience, stretched out of shape with wirepulling and putrefied with permeation.
Compromise need not mean cowardice. .."

John Fitzgerald Kennedy, "Profiles in Courage"


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